Skip to main content
. Author manuscript; available in PMC: 2015 Dec 4.
Published in final edited form as: Cell. 2014 Dec 4;159(6):1327–1340. doi: 10.1016/j.cell.2014.11.023

Figure 7. Environmental influence on enhancer landscapes in LPMs and microglia.

Figure 7

A. Effects of culture environment and 2μM ATRA chronic stimulation on the enhancer landscape of LPMs. B. UCSC browser images displaying effects of culture environment and 2μM ATRA chronic stimulation on H3K4me2, H3K27ac, and PU.1 binding at the Bhlhe40 locus in LPMs. C. Effects of culture environment and chronic stimulation with TGF-β1 on the enhancer landscape of LPMs. D. UCSC browser images displaying effects of culture environment and chronic stimulation with TGF-β1 on H3K4me2, H3K27ac, and PU.1 binding at the Ets1 locus in LPMs. E. Hierarchical model for mechanisms by which the peritoneal environment induces the enhancer landscape and gene expression signature of LPMs. See text for details. See also Table S7.