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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Biochim Biophys Acta. 2015 Jan 19;1848(5):1075–1080. doi: 10.1016/j.bbamem.2015.01.004

Table 1. Structure-activity analysis of symmetrical DMTU analogs.

Inhibitor Structure UT-A1 IC50 (mM) UT-B IC50 (mM)
1 graphic file with name nihms656916t1.jpg 6.6 ± 0.4 3.9 ± 0.6
2 graphic file with name nihms656916t2.jpg >25 >25
3 graphic file with name nihms656916t3.jpg 22 ± 1 14 ± 2
4 graphic file with name nihms656916t4.jpg >25 17 ± 2
5 graphic file with name nihms656916t5.jpg >25 >25
6 graphic file with name nihms656916t6.jpg >15 13 ± 2
7 graphic file with name nihms656916t7.jpg >25 >25
8 graphic file with name nihms656916t8.jpg >25 >25