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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Biochim Biophys Acta. 2015 Jan 19;1848(5):1075–1080. doi: 10.1016/j.bbamem.2015.01.004

Table 3. Structure-activity analysis of nitrophenyl and chlorophenyl thiourea analogs.

Inhibitor Structure UT-A1 IC50 (mM) UT-B IC50 (mM)
28 graphic file with name nihms656916t10.jpg 2.5 ± 0.5 >15
29 graphic file with name nihms656916t11.jpg >15 >15
30 graphic file with name nihms656916t12.jpg 2.0 ± 0.6 2.3 ± 0.2
31 graphic file with name nihms656916t13.jpg 9.3 ± 0.7 4.8 ± 1.3
32 graphic file with name nihms656916t14.jpg 0.2 ± 0.1 0.2 ± 0.1
33 graphic file with name nihms656916t15.jpg 0.3 ± 0.2 0.3 ± 0.1
34 graphic file with name nihms656916t16.jpg 0.8 ± 0.2 4.4 ± 0.6
35 graphic file with name nihms656916t17.jpg 1.6 ± 0.9 1.1 ± 0.4
36 graphic file with name nihms656916t18.jpg 3.4 ± 0.7 3.4 ± 0.8