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. 2015 Feb 21;15:77. doi: 10.1186/s12885-015-1069-4

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© Meneses-Echávez et al.; licensee BioMed Central. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Bubble plot for the dose–response relationship between the intervention length (weeks) and effect estimates changes for CRF from the nine randomized controlled trials included in the meta-regression analysis (P = 0.02).