Table 3.

Predictors of Quality of Life change ^a from baseline to follow-up, N=118 patients

Parameter	Bivariate analysis OR (95% CI)	P-value b	Multivariate analysis OR (95% CI)	P-value c
Age	1.00 (0.96 – 1.05)	0.862	–
Female gender	2.92 (1.12 – 6.71)	0.013	2.64 (1.12 - 6.22)	0.026
Education (years)	1.12 (0.92 –1.37)	0.269	–
Relationship status, single	1.14 (0.43 – 2.80)	0.778	–
Main diagnosis	0.93 (0.33 – 2.60)	0.891	–
Severity scores
Injection use	0.70 (0.31 – 1.53)	0.344	–
Years of using most problematic substance	1.0 (0.96 – 1.01)	0.737	–
Global Score Index: SCL-90R - GSI	1.72 (0.97 – 3.04)	0.064	1.52 (0.85-2.70)	0.157
Treatment variables
Days in treatment	1.01 (0.10 – 1.02)	0.334	–
Compulsory treatment	1.28 (0.56 – 2,94)	0.554
Follow-up variables
Abstinence at follow-up	1.51 (0.63 – 3.66)	0.356	–
Time in a controlled environment (days)d	1.03 (0.98 1.03)	0.86	–

^aThe dependent variable was a dichotomized QoL-5 score change, with a cut-off value of ≥ 0.2 (i.e., a large and clinically relevant QoL change).

^bP-value obtained from bivariate logistic regression.

^cP-value obtained from multivariable logistic regression; multivariable analysis included variables with p-values <0.20 in bivariate analyses.

^dTime in controlled environment last 30 days before follow-up interview.