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. 2015 Mar 17;10(3):e0118516. doi: 10.1371/journal.pone.0118516

Table 3. Catalytic proficiency of Rtt109-Vps75-mediated acetylation from histone titration (mean ± standard error).

Histone Titrated Residue Acetylated (kcat/Km)/knE(No unit) ΔΔG (kcal/mol)
H3 H3K9 (2.8 ± 1.5) x106 -9.1 ± 0.3
H3 H3K23 (7.3 ± 3.7) x105 -8.3 ± 0.3
H3/H4 H3K9 (2.0 ± 0.7) x105 -7.5 ± 0.2
H3/H4 H3K23 (2.1 ± 0.7) x105 -7.5 ± 0.2
H3/H4-Asf1 H3K9 (3.7 ± 1.2) x105 -7.9 ± 0.2
H3/H4-Asf1 H3K23 (2.9 ± 0.8) x105 -7.7 ± 0.2