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. 2014 Dec 23;14:209. doi: 10.1186/1471-2466-14-209

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© Beeh et al.; licensee BioMed Central. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Change from baseline in exercise endurance time at Week 3. Change from baseline in exercise endurance time during constant work rate cycle ergometry to symptom limitation at 75% of the maximum work rate was assessed at Week 3 (ITT population). Data reported as least squares means change from baseline (analysis of covariance) + standard error; Δ = least squares means difference (95% confidence interval). ^*p < 0.05 versus placebo. BID, twice daily; ITT, intent-to-treat.