Table 4.
The prognostic associations of KRAS mutation, BRAF mutation and MSI in right versus left colon in 121 patients with colon cancer
| Diseasestage II and III | All | |||||||
|---|---|---|---|---|---|---|---|---|
| Recurrence | No recurrence | Odds ratio (95% Confidence interval) | P | Disseminated¥ | Non-disseminatedβ | Odds ratio (95% Confidence interval) | P | |
| Rightcolon | ||||||||
| MSI | 5 | 12 | 0,40 (0,12-1,31) | 0,158 | 6 | 12 | 0,31 (0,10-0,95) | 0.055 |
| MSS | 22 | 21 | 34 | 21 | ||||
| Leftcolon | ||||||||
| MSI | 0 | 5 | * | 0,057 | 1 | 5 | 0,11 (0,01-1,04) | 0.069 |
| MSS | 15 | 15 | 27 | 15 | ||||
| Rightcolon | ||||||||
| BRAFmutation | 6 | 14 | 0,38 (0,12-1,21) | 0,168 | 10 | 14 | 0,45 (0,17-1,22) | 0.138 |
| BRAFwildtype | 21 | 19 | 30 | 19 | ||||
| Leftcolon | ||||||||
| BRAFmutation | 0 | 4 | * | 0,119 | 0 | 4 | 0.025 | |
| BRAFwildtype | 15 | 16 | 28 | 16 | * | |||
| Rightcolon | ||||||||
| BRAF/MSIpresent | 7 | 16 | 0,37 (0,12-1,12) | 0,110 | 11 | 16 | 0,40 (0,15-1,07) | 0.089 |
| BRAF/MSI absent | 20 | 17 | 29 | 17 | ||||
| Leftcolon | ||||||||
| BRAF/MSIpresent | 0 | 6 | * | 0,024 | 1 | 6 | 0,09 (0,01-0,79) | 0.015 |
| BRAF/MSI absent | 15 | 14 | 27 | 14 | ||||
| Rightcolon | ||||||||
| KRASmutation | 13 | 10 | 2,13 (0,74-6,16) | 0,157 | 20 | 10 | 2,3 (0,87-6,05) | 0.089 |
| KRASwildtype | 14 | 23 | 20 | 23 | ||||
| Leftcolon | ||||||||
| KRASmutation | 5 | 4 | 2,00 (0,43-9,27) | 0,451 | 14 | 4 | 4,00 (1,07-15,01) | 0.041 |
| KRASwildtype | 10 | 16 | 14 | 16 | ||||
βNon-disseminated: Disease stage II and III without recurrence; ¥Disseminated: Disease stage II and III with recurrence and stage IV. *Not able to calculate OR because of 0 in one grupp.