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. 2015 Mar 19;16:8. doi: 10.1186/s12867-015-0038-4

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© Dean et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Ets1 and Zeb1 are expressed at the invasive front of K-Ras initiated mouse lung adenocarcinoma. (A and B) H&E staining showing the invasive front of an adenocarcinoma (AC) from a K-Ras^LA1 mouse lung. (C-E) Note immunostaining for E-cadherin (E-cad.) in normal lung and expression of Zeb1 and Est1 in carcinoma invading into normal lung. Arrows indicate invasive carcinoma.