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. 2015 Mar 15;5:11. doi: 10.1186/s13578-015-0003-4

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© Li et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Exogenous hydrogen sulfide involved in recovery of PC-induced cardioprotection in isolated aging rat hearts. Exogenous H₂S recovers PC-induced cardioprotection by up-regulating PI3K-Akt-GSK-3β pathway and inhibiting oxidative stress in the aging rats.