Table 1. Demographics, risk factors, neurologic symptoms, and location of CC infarction.
| CC infarction | Genu and/or body infarction | splenium infarction | p value (genu and/or body infarction versus splenium infarction) | genu | body | genu and body | genu and body and splenium | |
|---|---|---|---|---|---|---|---|---|
| Cases,n (%) | 59 (100) | 23 (40.0) | 26 (44.1) | 8 (13.5) | 7 (11.9) | 8 (13.6) | 10 (16.9) | |
| Age | 68.4±11.5 | 67.9±11.7 | 70.6±10.6 | 0.398 | 71.3±10.4 | 64.6±15.5 | 67.4±9.5 | 63.7±12.8 |
| Gender (male), n (%) | 35 (59.3) | 12 (52.2) | 15 (57.7) | 0.778 | 3 (37.5) | 4 (57.1) | 5 (62.5) | 8 (80.0) |
| Risk factors, n (%) | ||||||||
| Hypertension | 44 (74.5) | 18 (78.3) | 19 (73.1) | 0.748 | 7 (87.5) | 5 (71.4) | 6 (75.0) | 7 (70.0) |
| Diabetes mellitus | 29 (49.2) | 11 (47.8) | 15 (57.7) | 0.572 | 4 (50.0) | 3 (42.9) | 4 (50.0) | 3 (30.0) |
| Dyslipidemia | 32 (54.2) | 12 (52.2) | 15 (57.7) | 0.778 | 5 (62.5) | 3 (42.9) | 4 (50.0) | 5 (50.0) |
| Heart diseases | 21 (35.6) | 11 (47.8) | 8 (30.8) | 0.254 | 4 (50.0) | 2 (28.6) | 5 (62.5) | 2 (20.0) |
| Excessive drinking | 15 (25.4) | 6 (26.1) | 6 (23.1) | 1.000 | 2 (25.0) | 2 (28.6) | 2 (25.0) | 3 (30.0) |
| Current smoking | 20 (33.9) | 8 (34.8) | 8 (30.8) | 1.000 | 3 (37.5) | 3 (42.9) | 2 (25.0) | 4 (40.0) |
| Prior stroke or TIA | 14 (23.7) | 5 (21.7) | 8 (30.8) | 0.532 | 0 (0) | 3 (42.9) | 2 (25.0) | 1 (10.0) |
| Family history of stroke | 2 (3.4) | 1 (4.3) | 0 (0) | 0.469 | 0 (0) | 0 (0) | 1 (12.5) | 1 (10.0) |
| Atheroma of ICA | 54 (91.5) | 22 (95.7) | 23 (88.5) | 0.000 ** | 8 (100) | 7 (100) | 7 (87.5) | 9 (90.0) |
| Atheroma of vertebrobasilar artery | 25 (42.4) | 9 (39.1) | 12 (46.2) | 5 (62.5) | 1 (14.3) | 3 (37.5) | 4 (40.0) | |
| Neurologic manifestation, n (%) | ||||||||
| Hemiparesis | 43 (72.9) | 17 (73.9) | 17 (65.4) | 0.552 | 5 (62.5) | 5 (71.4) | 7 (87.5) | 9 (90.0) |
| Sensory abnormality | 19 (32.2) | 4 (17.4) | 11 (42.3) | 0.071 | 1 (12.5) | 1 (14.3) | 2 (25.0) | 4 (40.0) |
| Ataxia | 6 (10.1) | 3 (13.0) | 3 (11.5) | 1.000 | 1 (12.5) | 0 (0) | 2 (25.0) | 0 (0) |
| Aphasia | 10 (16.9) | 6 (26.1) | 2 (7.7) | 0.125 | 2 (25.0) | 1 (14.3) | 3 (37.5) | 2 (20.0) |
| Dysarthria | 13 (22.0) | 4 (17.4) | 7 (26.9) | 0.506 | 1 (12.5) | 1 (14.3) | 2 (25.0) | 2 (20.0) |
| Alien hand syndrome | 2 (3.4) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 2 (20.0) | |
| Disturbance of consciousness | 6 (10.1) | 0 (0) | 5 (19.2) | 0.052 | 0 (0) | 0 (0) | 0 (0) | 1 (10.0) |
| Admission time after the onset(hours) | 42.9±47.0 | 44.0±36.8 | 44.2±59.1 | 0.240 | ||||
| Bilateral cerebral hemisphere involvement | 19 (32.2) | 4 (17.4) | 12 (46.2) | 0.039 * | ||||
| Initial NIH Stroke Scale score | 3.0±3.7 | 2.7±3.1 | 3.1±4.3 | 0.691 | ||||
| Discharge NIH Stroke Scale score | 3.1±4.0 | 3.7±3.4 | 2.8±4.8 | 0.155 | ||||
Normally distributed numerical variables: Student’s t–test; non-normally distributed numerical variables: non-parametric test (Wilcoxon rank-sum test); categorical variables: chi-squared test.
*p<0.05.
TIA = Transient cerebral ischemia. ICA = internal carotid artery. Values are number (%) or mean±standard deviation
**Comparision of atheroma between genu and/or body and splenium group with their supplying artery respectively