Table 1. Summary of the reactions and parameters involved in the lumped AA and LA metabolism under investigation.

No.	Reaction	Control enzyme	Parameter name
1	AA → 5(S)-HETE	5-LOX, FLAP	k 1
2	AA → 15(S)-HETE	15-LOX	k 2
3	AA → 11,12-DiHETrE	CYP, sEH	k 3
4	AA → 14,15-DiHETrE	CYP, sEH	k 4
5	LA → 9(S)-HODE	15-LOX	k 5
6	LA → 9,10-DiHOME	CYP, sEH	k 6
7	LA → 13(S)-HODE	15-LOX	k 7
8	5(S)-HETE→		k 8
9	15(S)-HETE →		k 9
10	11,12-DiHETrE →		k 10
11	14,15-DiHETrE →		k 11
12	9(S)-HODE →		k 12
13	9,10-DiHOME →		k 13
14	13(S)-HODE →		k 14