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. 2015 Mar 18;10(3):e0119850. doi: 10.1371/journal.pone.0119850

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© 2015 Portovedo et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 1 — A. Weight gain of mice fed a high fat diet compared to chow for 16 weeks. QRT-PCR was used to analyze the gene expression of B. IL1-β, C. TNFR1 and D. IL-10 in the hypothalamus of DIO mice at 8 weeks of treatment. QRT-PCR was used to analyze the gene expression of E. IL1-β, F. TNFR1 and G. IL-10 in the hypothalamus of DIO mice at 16 weeks of treatment. Values are shown as mean ± SEM. *P < 0.05; n = 6 animals per group.