Fig 4. Kaplan-Meier survival curves of mice carrying either Ramos or Granta xenografts after ¹⁷⁷Lu-/ ⁹⁰Y-PRIT.

Athymic nude mice were i.v. injected with 300 μg of 1F5-SA or HB8181-SA, together with 400 μg of HB8181, followed 20 hours later by 50 μg of NAGB. Four hours later, ¹⁷⁷Lu- or ⁹⁰Y-labeled DOTA-biotin was administered: 15, 30, or 37 MBq for Ramos xenografts; 37 MBq for Granta (n = 10). Control groups received no treatment (PBS only).