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Changes in (a) hemoglobin A1c (HbA1c), (b) fasting plasma glucose and (c) bodyweight from baseline to the end of treatment with last observation carried forward. Light bars, 100 mg canagliflozin; dark bars, 200 mg canagliflozin. Values are means ± standard deviation. α-GI, α-glucosidase inhibitor; DPP-4, dipeptidyl peptidase-4 inhibitor; NGSP, National Glycohemoglobin Standardization Program; SU, sulfonylurea; TZD, thiazolidinedione.
