Table 2.
Survival times for transgenic mice following intracerebral challenge with the RML isolate of mouse-adapted prions
Mouse genotype | Genetic background | Mean survival ± SEM | N |
---|---|---|---|
TgPrP(S3.F88W)-35 | FVB Prnp0/0 | 84.1 ± 2.6 | 12 |
TgPrP(S3.F88W)-14 | FVB Prnp0/0 | 89.1 ± 2.5 | 16 |
TgPrP(S1)-17 | FVB Prnp0/0 | 139.1 ± 2.8 | 22 |
TgPrP(S1)-19 | FVB Prnp0/0 | 152.5 ± 2.5 | 17 |
TgPrP(S1)-39 | FVB Prnp0/0 | 424.4 ± 9.2 | 9 |
TgPrP(WT) | FVB Prnp0/0 | 398.3 ± 8.1 | 12 |
WT | FVB | 155.9 ± 2.0 | 16 |