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. 2015 Mar 18;10(3):e0119918. doi: 10.1371/journal.pone.0119918

Fig 3. Characterization of NOS isoforms in the lungs of LPS exposed mice.

Fig 3

Lung protein extracts were subjected to immunoblot analysis using specific antisera raised against neuronal nitric oxide synthase (nNOS) or inducible nitric oxide synthase (iNOS). Neuronal NOS was not detected in the lungs of either wild-type or eNOS-/- mice (A). The protein levels of iNOS were significantly higher in the lungs of wild-type and eNOS-/- mice treated with LPS; however, the LPS induced increase in iNOS levels in the lungs of eNOS-/- mice was significantly less than in the wild-type mice (B). Values are mean ± SEM, n = 6–9. *p<0.05 vs. Wild-type+Vehicle, †P<0.05 vs. Wild-type+LPS.