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. 2015 Mar 13;20(1):639–648. doi: 10.2119/molmed.2014.00076

Figure 1.

Figure 1

Pharmacological inhibition of TLR4 with eritoran protects against liver I/R injury. (A) Sham or I/R-treated mice were given eritoran (5 mg/kg body weight) or vehicle control intraperitoneally 30 min before ischemia. Data represent the mean ± SEM (n ≥ 6 mice per group). Gray, eritoran; black, control. *P < 0.05, by one-way ANOVA. (B) Quantification of necrotic hepatocytes in H&E-stained liver sections from sham, control and eritoran-treated animals 6 h after reperfusion. The graph is representative of liver sections from three or more mice per group. *P < 0.05, by one-way ANOVA.