TABLE 1.
Cox1 sequence alignment of a U.S. Diphyllobothrium isolate compared to sequences of other Diphyllobothrium spp. by ClustalW
| Isolate (GenBank accession no.)a | Sequence alignmentb by cox1 gene position: |
|||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 663 | 669 | 678 | 684 | 717 | 720 | 723 | 756 | 765 | 792 | 795 | 801 | 807 | 825 | 846 | 855 | |
| U.S. isolate | C | A | A | C | C | C | C | A | C | A | T | T | G | T | C | T |
| D. nihonkaiense (AB684623.1) | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X |
| D. klebanovskii (AB375661.1) | X | X | X | T | X | T | X | X | X | X | X | X | X | C | X | X |
| D. nihonkaiense Dn8 (AB375003.1) | X | X | X | T | X | T | X | X | X | X | C | X | X | X | X | X |
| D. latum (AB504899.1) | T | G | G | T | T | T | T | G | G | T | X | C | A | X | T | A |
a
Sample D. nihonkaiense Dn8 (GenBank accession no. AB375003.1) was determined by the Hashimoto group to be of a distinct lineage closely related to D. klebanovskii. The D. latum sequence was included as a reference.
b
X, homology with the U.S. isolate sequence.