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. 2015 Mar 18;53(4):1183–1191. doi: 10.1128/JCM.03531-14

TABLE 2.

Detection rates by species group for each of the studies included in our analysis

First author, yr (reference) Detection rate (no. of patients) among species groupa
E. coli
Non-E. coli Enterobacteriaceae
P. aeruginosa
Non-GN bacteremia
TP FN TP FN TP FN FP TN
Ahmed, 2004 (4) 1 0 0 0 3 0 12 19
Bailey, 1976 (5) 1 0 0 0 0 0 12 11
Bion, 1994 (6) 0 0 0 0 1 1 31 19
Byl, 2001 (7) 6 2 0 0 0 0 3 12
Clumeck, 1977 (8) 5 3 0 0 2 0 2 34
Cooperstock, 1985 (9) 3 0 0 0 1 1 6 26
Danner, 1991 (10)b 5 4 1 3 2 0 32 49
Dofferhoff, 1992 (11) 1 1 1 1 2 0 6 6
Engervall, 1997 (12) 1 0 0 1 1 1 4 14
Feldman, 1974 (13) 0 9 0 4 2 10 0 53
Fossard, 1974 (14) 1 0 0 0 1 0 22 1
Garcia Curiel, 1979 (15) 0 3 1 10 0 1 3 23
Giamarellos-Bourboulis, 1999 (16)b 2 8 1 1 0 0 4 9
Goldie, 1995 (17)b 1 1 3 1 2 0 83 38
Guidet, 1994 (18)b 9 7 5 0 0 0 20 40
Hass, 1986 (19) 0 0 0 0 2 0 8 25
Hynninen, 1995 (20) 1 0 1 0 0 0 0 96
Jirillo, 1975 (21) 0 0 1 1 0 0 4 4
Kelsey, 1982 (22) 0 1 0 0 1 0 0 28
Ketchum, 1997 (23)b 3 20 5 22 2 3 109 198
Kritselis, 2013 (24)b,c 6 56 9 45 1 23 13 188
Kritselis, 2013 (24)b,c 25 37 24 30 15 9 66 135
Lau, 1996 (25) 5 3 1 0 0 0 20 9
Levin, 1970 (26) 0 2 0 5 2 1 7 76
Levin, 1972 (27) 4 3 6 10 6 1 19 168
Martinez, 1973 (28) 1 3 0 3 1 0 1 66
Massignon, 1996 (29) 9 2 3 0 3 1 21 16
McCartney, 1987 (30) 0 1 0 0 0 0 8 17
Oberle, 1974 (31) 0 0 1 0 2 0 6 14
Opal (high), 1999 (32)b,c 18 21 15 18 16 15 241 383
Opal (low), 1999 (32)b,c 33 6 27 6 24 7 496 128
Pearson, 1985 (33) 5 0 1 1 0 0 2 32
Prins, 1995 (34)b 4 5 0 0 1 0 2 18
Scheifele, 1985 (35) 0 1 0 0 0 0 20 22
Shenep, 1988 (36) 0 1 2 0 1 0 3 13
Strutz, 1999 (37) 4 4 1 0 0 1 8 10
Stumacher, 1973 (38) 7 11 10 18 2 4 26 48
Suyasa, 1995 (39) 0 0 0 0 4 0 0 9
Togari, 1983 (40) 0 0 1 0 0 0 7 2
Van Deventer, 1988 (41) 7 2 4 0 0 0 14 406
Van Dissel, 1993 (42) 2 0 2 0 0 0 7 3
Watzke, 1987 (43) 0 0 3 1 1 0 4 11
Wong, 2013 (44) 8 0 5 0 1 0 89 0
Yoshida, 1993 (45)b 1 0 6 5 4 3 35 71
a

Abbreviations: TP, true positive, the number of patients with endotoxemia and Gram-negative bacteremia; FP, false positive, the number of patients with endotoxemia and without Gram-negative bacteremia; FN, false negative, the number of patients without endotoxemia and with Gram-negative bacteremia; TN, true negative, the number of patients with neither endotoxemia nor Gram-negative bacteremia. Patients with polymicrobial bacteremia were not included in the analysis.

b

Data provided via personal communication with the study author.

c

For two studies (24, 32), there is a double entry of data in the table because patients were analyzed at both high and low endotoxemia detection breakpoints. In the HSROC analysis (Table 3; Fig. 2 and 3), the study weights for the data for each breakpoint from these two studies were halved.