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Distribution and intensity of LMP-1 expression in MTX-/Age-EBV-LPDs and DLBCLs in biopsy specimens. ((a)–(c)) HE stain and ((d)–(f)) LMP-1 by IHC. LMP-1 positive atypical lymphoid cells (brownish color) were diffuse or sporadic diffuse in (d) MTX-LPD or (e) Age-LPD but were not verifiable in (f) DLBCL. LMP-1 positive cells were of moderate or strong intensity in (d) MTX-LPD and (e) Age-LPD and were of weak or nonspecific intensity in (f) DLBCL ((a)–(f) original magnification, ×200).
