Table 3.
Major mitochondrial genome mutations in different types of total atherosclerotic lesion of morphologically mapped aortas.
| Mutations | Primary total atherosclerotic lesion | Lipofibrous plaques | Fibrous plaques | |||
|---|---|---|---|---|---|---|
| Correlation coefficient | Asymptomatic significance | Correlation coefficient | Asymptomatic significance | Correlation coefficient | Asymptomatic significance | |
| 652delG | 0.093 | 0.146 | 0.308* | 0.091* | 0.323* | 0.071* |
| 652insG | −0.075 | 0.186 | −0.095 | 0.125 | −0.058 | 0.232 |
| A1555G | −0.359** | 0.048** | −0.401** | 0.039** | −0.084 | 0.195 |
| C3256T | 0.368** | 0.045** | 0.407** | 0.045** | 0.352** | 0.050** |
| T3336C | 0.426** | 0.034** | 0.437** | 0.025** | 0.103 | 0.119 |
| C5178A | 0.365** | 0.046** | 0.439** | 0.023** | 0.356** | 0.048** |
| G12315A | 0.353** | 0.050** | 0.409** | 0.041** | −0.367** | 0.046** |
| G13513A | −0.423** | 0.035** | −0.437** | 0.021** | 0.095 | 0.143 |
| G14459A | 0.403** | 0.042** | 0.463** | 0.026** | 0.073 | 0.191 |
| G14846A | −0.107 | 0.117 | −0.351** | 0.050** | 0.052 | 0.214 |
| G15059A | 0.405** | 0.043** | 0.471** | 0.015** | 0.062 | 0.203 |
*Correlation of mutations with atherosclerotic lesions at P ≤ 0.1 level of significance; **significant correlation of mutations with atherosclerotic lesions (P ≤ 0.05).