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. 2015 Mar 5;2015:418362. doi: 10.1155/2015/418362

Table 2.

Antimicrobial activity (IC50s and MICs in µM [mg/mL]) of boric acid and 35 against Candida albicans, Staphylococcus aureus, and methicillin resistant S. aureus.

Compounds C. albicans S. aureus MRSA
IC50; SEM1 MIC2 IC50; SEM MIC IC50; SEM MIC
B(OH)3 Inactive3 Inactive Inactive Inactive Inactive Inactive

CAPE (3) 132.43; 0.40 176 39.1; 1.10 86 12.3; 1.50 86
[37.65; 0.11] [50] [11.12; 0.32] [25] [3.5; 0.40] [25]

4 72.2; 0.70 125 19.93; 1.45 42 22.9; 1.50 84
[43.22; 0.40] [75] [11.93; 0.87] [25] [13.71; 0.88] [50]

5 146.10; 1.50 >245 Inactive Inactive 11.35; 1.10 61
[119.50; 1.20] [>200] [9.28; 0.88] [50]

1IC50s estimated by probit analysis. 2MIC (minimum inhibitory concentration) is defined as the lowest concentration that showed over 90% inhibition. 3Less than 50% inhibition in initial screening (at 100 μg/mL) is considered to be inactive.