Table 3. The identified DNBs are the modules with high influence appearing in both the control and case networks at each time point for the four datasets. The common genes identified by other methods were noted in bold.

Datasets	Modules	Genes in the corresponding module
GSE30550	HM1	{DDX58; HERC5; HERC6; IFI27; IFI35; IFI44; IFI44L; IFI6; IFIH1; IFIT1; IFIT2; IFIT3; IRF7;IRF9;ISG15;MX1;OAS1;OAS2;OAS3; OASL; RSAD2; XAF1}
GSE52428	HM2	{ADAR; DDX58; GBP1; GBP2; HERC5; HERC6; IFI27; IFI35; IFI44; IFI44L; IFI6; IFIH1; IFIT1; IFIT2; IFIT3; IFIT5; IFITM1; IRF1; IRF7; IRF9; ISG15; MX1; MX2; OAS1; OAS2; OAS3; OASL; RSAD2; RTP4; XAF1}
GSE2565	HM3	{Bnip3; Esd; Hk2; Aldoa; Ldha; Pgd; Pgk1; Pkm2; Taldo1; Tkt; Tpi1;Arhgef12; Pard6b; Prkci; Rhoj; Rhou; Pkp3; Ppl; Scel; Gtf2f2; Pcf11; Papolg; Ptbp1; Thoc4; U2af1}
GSE13268	HM4	{Akr1b7; Fah; Glrx1; Gpx7; Gss; Gsta3; Gstm2; Gstm5; Gstm7; Gsto1; Gsto2; Gstp1; Gstt1; Gstt2; Mgst2;Nit1; Prdx3; Xdh; Ankrd6; Frzb; Fzd1; Acpl2; Lef1; Nkd1; NlkSox17; C6; Ermp1; Ppap2c; Sgms1; Smpd2; Smpd3; Cyp11a1; Cyp11b1; Tmem50b; Hsd11b2; Fdx1l}