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. 2015 Mar 19;3:24. doi: 10.3389/fbioe.2015.00024

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Copyright © 2015 Lee, Richtsmeier and Kraft.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Procedure for constructing a computational domain. (A) An isosurface of the cranial vault bones from a three-dimensional reconstruction of micro CT images acquired from a mouse at E17.5 was used for making the domain and generating a mesh. Rostral end (nose) is toward the top while the caudal end of the skull is at bottom. (B) Only parts of cranial vault are considered. (C) Surface surrounding the cranial vault is made. (D) Shell-shaped domain around the surface and mesh are generated.