Table 1.
Characteristics of healthy subjects in the baseline night of simulated ICU noise and light (Baseline NL)
| Variable | NI | NIP | NLEE | NLM | P |
|---|---|---|---|---|---|
| Age | 42.8 ± 11.8 | 39.7 ± 11.6 | 40.1 ± 12.7 | 42.0 ± 12.8 | 0.930 |
| Gender (percent female) | 0.4 | 0.5 | 0.5 | 0.6 | 0.849 |
| Time in bed (min) | 520.6 ± 17.0 | 509.1 ± 16.4 | 511.8 ± 17.8 | 510.9 ± 26.6 | 0.580 |
| Total sleep time (min) | 349.2 ± 28.4 | 354.0 ± 22.6 | 354.2 ± 20.7 | 348.6 ± 22.0 | 0.922 |
| Sleep efficiency index | 0.69 ± 0.08 | 0.75 ± 0.08 | 0.72 ± 0.07 | 0.75 ± 0.05 | 0.164 |
| REM (%) | 16.6 ± 3.6 | 16.5± 6.3 | 18.5 ± 3.5 | 19.3 ± 4.1 | 0439 |
| N1 (%) | 17.7 ± 3.9 | 18.8 ± 3.3 | 19.6 ± 2.3 | 19.6 ± 3.2 | 0.530 |
| N2 (%) | 47.9 ± 6.3 | 47.5 ± 7.1 | 46.2 ± 1.6 | 43.6 ± 3.4 | 0.259 |
| N3 (%) | 15.8 ± 3.5 | 17.2 ± 4.9 | 15.7 ± 2.8 | 17.5 ± 3.5 | 0.620 |
| Sleep onset latency (min) | 58.4 ± 15.5 | 54.3 ± 15.3 | 53.2 ± 16.9 | 46.9 ± 11.0 | 0392 |
| REM latency (min) | 166.6 ± 38.8 | 140.4 ± 29.3 | 159.5 ± 30.0 | 154.4 ± 37.5 | 0381 |
| No. of awakenings | 14.4 ± 3.3 | 14.4 ± 3.1 | 13.5 ± 2.8 | 13.8 ± 3.0 | 0.885 |
| Sleep arousals index | 8.7 ± 3.3 | 8.4 ± 2.4 | 8.2 ± 1.3 | 8.4 ± 2.1 | 0.981 |
| State anxiety | 46.0 ± 8.8 | 45.2 ± 7.7 | 44.4 ± 5.9 | 45.0 ± 5.9 | 0.968 |
| Sleep quality | 6.1 ± 1.0 | 5.9 ± 1.0 | 6.1 ± 1.3 | 6.2 ± 1.4 | 0.952 |
NL: simulated ICU noise and light; NLP: NL plus placebo; NLM: NL plus melatonin; NLEE: NL plus use of earplugs and eye masks.