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. 2014 Dec 23;66(4):545–554. doi: 10.1111/his.12554

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© 2014 The Authors. Histopathology published by John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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A, A biopsy specimen from the superior segment of the left upper lobe taken from a patient aged 61 years, showing a typical feature of pleuroparenchymal fibroelastosis [elastica van Gieson (EVG)]. B, A biopsy specimen from right S2 taken at the age of 49 years, showing cellular interstitial pneumonia with localized areas of subpleural fibrosis [haematoxylin and eosin (H&E)]. C, Higher magnification of (B) (indicated by a black arrow), showing a granuloma with giant cells adjacent to the subpleural fibrosis (H&E). D, EVG staining of the sample shown in (B), revealing subpleural fibrosis consisting of fibroelastosis.