Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Adverse effects
RCT	43 people starting treatment with allopurinol for chronic gouty arthritis	Diarrhoea 38% with allopurinol plus colchicine 5% with allopurinol plus placebo Absolute numbers not reported	P = 0.009	Effect size not calculated	allopurinol plus placebo