Table 1. Melting temperatures for AAV2 and AAV5 VLPs treated with Gd and Gab.

Treatment	Tm (°C)
AAV2 + PBS	67.53 ± 0.3
AAV2 + PBS + 2 mmol/l Gd	67.4 ± 0
AAV2 + PBS + 0.2 mmol/l Gab	66.2 ± 0.2
AAV2 + lactated Ringer’s solution	75.7 ± 0.7
AAV2 + lactated Ringer’s solution + 2 mmol/l Gd	77.8 ± 0.6
AAV2 + lactated Ringer’s solution + 0.2 mmol/l Gab	77.3 ± 0.4
AAV5 + PBS	89.8 ± 0.1
AAV5 + PBS + 2 mmol/l Gd	89.5 ± 0.4
AAV2 + PBS + 0.2 mmol/l Gab	90.0 ± 0.1
AAV5 + lactated Ringer’s solution	90.3 ± 0.2
AAV5 + lactated Ringer’s solution + 1mmol/l Gd	90.5 ± 0.1
AAV5 + lactated Ringer’s solution + 0.2 mmol/l Gab	90.4 ± 0.2

AAV, adeno-associated virus; Gab, galbumin; Gd, gadoteridol;

PBS, phosphate-buffered saline.