Fig 1.

Accelerated clearance of erythrocytes in APC-deficient mice. Time-dependent decay of CFSE-labelled circulating erythrocytes drawn from 20-week-old APC-deficient mice (black squares) and wild-type mice (black diamonds) and injected into the same mice. The percentage of CFSE-labelled circulating cells is plotted against time after injection. Values are normalized arithmetic mean ± S.E.M. (n =4) of the percentages of CFSE-labelled erythrocytes. * indicates significant difference between genotypes (Mann–Whitney test; P < 0.05).