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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Arthritis Rheumatol. 2014 Jun;66(6):1666–1671. doi: 10.1002/art.38379

Figure 1.

Figure 1

Murine and human hemophagocytes. (A) Laser capture microdissection of a resting murine splenic macrophage and (B) a murine HPC. (C & D) HPCs from a heterogeneous cohort express CD163, and rarely CD206 or CD64. (C) Positive controls for immunohistochemical stains in tonsil tissue from patients without hemophagocytic disease. (D) Bone marrow biopsies from representative patients with hemophagocytic disease immunostained for CD163, CD206, or CD64 as detailed in Materials and Methods. All images are 100X magnification and slides are counterstained with hematoxylin.