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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Semin Nucl Med. 2015 Mar;45(2):163–176. doi: 10.1053/j.semnuclmed.2014.10.004

Table 2.

Known 1-electron Nitroreductases and substrate Km’s

Name Origin Km for CB1954* (mM) Reference
NfsA E Coli 0.22 (55)
NfsB E Coli 3.6 (55)
NemA E Coli 0.06 (55)
POR mammalian ND (56, 63)
MTRR mammalian ND (56)
NDOR1 mammalian ND (56)
NOS2A mammalian ND (56)
*

Similar values have been found using EF5 as substrate (A.V. Patterson, personal communication)