Table 1.
Summary of the 12 SNPS in the genetic panel investigated in this study, and their reported associations to breast cancer
| SNP | Gene | Associations to breast cancer |
|---|---|---|
| rs1045485 | CASP8 | Associated with overall breast cancer risk [39] |
| rs11249433 | 1p11 | Associated with ER+ breast cancer [45,47] |
| rs1219648 | FGFR2 | Associated with overall and ER+ breast cancer risk [43,48] |
| rs13281615 | 8q24 | Associated with ER+, PR+, and low grade tumors [44] |
| Associated with survival after diagnosis [44] | ||
| rs13387042 | 2q35 | Associated with ER+ risk [40] |
| rs3803662 | TNRC9/TOX3 | Associated with ER+ cancer risk and metastatic disease [40] |
| Associated with an earlier age at diagnosis [49] | ||
| rs3817198 | LSP1 | Associated with overall breast cancer risk [41] |
| rs4415084 | MRPS30 | Associated with ER+ breast cancer [43] |
| rs4973768 | NEK10 | Associated with overall breast cancer risk [46] |
| rs6504950 | COX11/STXBP4 | Associated with overall breast cancer risk [46] |
| rs889312 | MAP3K1 | Associated with overall and ER- breast cancer risk [41,44] |
| rs999737 | RAD51L1 | Associated with overall breast cancer risk [45] |
The related bibliographic references for each SNP are included in brackets.