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. 2015 Mar 19;56(3):1956–1964. doi: 10.1167/iovs.14-16144

Figure 4.

Figure 4

PF-4var/CXCL4L1 reduces the expression of HIF-1α and VEGF in diabetic rat retinas. The expression of HIF-1α was quantified by Western blot analysis and adjusted to the expression of β-actin in each sample, followed by normalization to values of normal eyes. Total VEGF levels were measured in rat retinal tissue homogenates by sandwich ELISA with 150 μg protein. Each sample was measured in duplicate, and eight or more rats were included in each group. N, normal; D+PBS, PBS-injected diabetic eye; D+PF-4var/CXCL4L1, PF-4var/CXCL4L1-injected diabetic eye. *P < 0.05 compared to normal, #P < 0.05 compared to diabetes.