Fig. 1. Natural killer cell frequency and subset distribution in cord blood of HIV-1 uninfected infants grouped by subsequent HIV-1 acquisition.
Cord blood mononuclear cells were gated on singlets and live cells prior to exclusion of CD3+ and CD20+ lymphocytes. NK cells subsets were defined by the expression of surface markers CD56 and/or CD16 (a). The proportion of CD3−CD20− cells defined as NK cells found in cases and controls (b). The median frequencies of the phenotypic distribution of NK cell subsets shown for controls and cases (c). Detailed distribution of individual data points for comparison of NK cell subsets between controls and cases (d). Lines represent the medians for a given subset. Statistics were generated via a Mann–Whitney test (*P <0.05).