Table 4.

HPV DNA type prevalence in subjects with recurrent respiratory papillomatosis.

Study [Reference code] (see Table 5)	Country	HPV detection method	N infections	HPV prevalence N (%)
Study [Reference code] (see Table 5)	Country	HPV detection method	N infections	Any HPV	Multiple infection	HPV-6	HPV-11	HPV-16	HPV-18	HPV-31	HPV-33	HPV-35	HPV-39
Gomez MA et al. 1995 [Table 5: d1]	Argentina	PCR MY09-11/nested GP5-6	12	12 (100%)	-	7		-	-	-	-	-	-
Gomez MA et al. 1995 [Table 5: d1]	Argentina	PCR MY09-11/nested GP5-6	12	12 (100%)	-	58%		-	-	-	-	-	-
Levi JE et al. 1989 [Table 5: d2]	Brazil	PCR MY09-11	19	19 (100%)	1 (5%)	14 (74%)	3 (16%)	-	-	-	-	-	-
Draganov P et al. 2006 [Table 5: d3]	Bulgaria	PCR MY09-11/TS primers 6,11,16,18,31,33	23	21 (91%)	3 (13%)	8 (35%)	16 (70%)	0	0	0	0	-	-
Fu M et al. 2000 [Table 5: d4]	China	PCR (HPV-L1 region primers)	13	13(100%)	0	8 (62%)	4 (31%)	0	1 (8%)	0	-	-	-
Sun AK 1993 [Table 5: d5]	China	In situ hybridization	45	36 (80%)	-	17 (38%)	19 (42%)	0	-	-	-	-	-
Lindeberg J et al. 1990 [Table 5: d6]	Denmark	Not given	20	19 (95%)	-	19		0	0	-	-	-	-
Lindeberg J et al. 1990 [Table 5: d6]	Denmark	Not given	20	19 (95%)	-	95%		0	0	-	-	-	-
Dickens P et al. 1991 [Table 5: d7]	Hong Kong	PCR (primer not given)	27	16 (59%)	3 (5%)	3 (5%)	16 (22%)	3 (5%)	0	-	-	-	-
Velyvyte D et al. 2002 [Table 5: d8]	Lithuania	PCR (4 different primers)	36	35 (97%)	17 (47%)^a	32		18 (50%)	3 (8%)	0	0	0	0
Velyvyte D et al. 2002 [Table 5: d8]	Lithuania	PCR (4 different primers)	36	35 (97%)	17 (47%)^a	89%		18 (50%)	3 (8%)	0	0	0	0
Peñaloza-Plasencia M et al. 2000 [Table 5: d9]	Mexico	PCR CPI/CPIIG (E1)	47	47 (100%)	35 (74%)	15 (32%)	18 (38%)	39 (83%)	0	2 (4%)	26 (55%)	13 (28%)	7 (15%)
Obchinnikov IuM et al. 2004 [Table 5: d10]	Russia	PCR (primers not reported)	26	26 (100%)	4 (15%)	11 (42%)	19 (73%)	0	0	-	-	-	-
Padayachee A et al. 1993 [Table 5: d11]	South Africa	Not given	20	20 (100%)	0	5 (25%)	15(75%)	0	0	-	-	-	-
Szeps M et al. 2005 [Table 5: d12]	Sweden and Finland	PCR GP5+/6+, TS primer 6/11/16/18/33	25	20 (80%)	-	12 (48%)	6 (24%)	0	0	-	0	-	-
Ushikai M et al. 1994 [Table 5: d13]	Thailand	Dot blot analysis/ PCR	25	22 (88%)	-	1 (4%)	21(84%)	0	0	-	-	-	-
Maloney EM et al. 2006 [Table 5: d14]	USA	PCR TS primers HPV 6,11, 16, 18	15	15 (100%)	7 (47%)	11(73%)	11(73%)	0	0	-	-	-	-
Rabah R et al. 2001 [Table 5: d15]	USA	PCR TS primers HPV 6,11, 16, 18	61	61 (100%)	0	29 (48%)	32 (52%)	0	0	-	-	-	-
Pou AM et al. 1995 [Table 5: d16]	USA	PCR TS primer 6,11,16,18, 31,33	24 of 29 typed	24 (100%)	-	21 (88%)	2 (8%)	1 (4%)	0	0	0	-	-
Bello de Alford M et al. 2001 [Table 5: d17]	Venezuela	PCR (primers not reported)	15	8 (53%)	-	4		0	0	0	0	0	-
Bello de Alford M et al. 2001 [Table 5: d17]	Venezuela	PCR (primers not reported)	15	8 (53%)	-	27%		0	0	0	0	0	-

HPV-6/11 considered as single infection when counting at multiple infections.

N Infections: Number of subjects with HPV DNA typed from the recurrent respiratory papillomatosis except for Lindeberg J et al. [Table 5: d6], where 16 subjects had 20 papillomas investigated.

GP: General primer; PCR: Polymerase chain reaction; TS: Type-specific primer.

Sources of data: [Table 5: d1–d17].