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. 2015 Mar 19;10(3):e0116096. doi: 10.1371/journal.pone.0116096

Table 2. Genes in Tsc1 null MEFs scoring positive in one of three replicates.

Gene Symbol GeneID Functional class
Fkbp5 14229 chaperone
Fkbp6 94244 chaperone
Actg2 11468 cytoskeleton-actin
Gmfg 63986 cytoskeleton-cofilin family
Smc1a 24061 DNA structure
Mcm3 17215 DNA-replication
Gpr82 319200 GPCR-lower food intake in KO
Gpr147 237362 GPCR-neuropeptide FF
Avpr1B 26361 GPCR-AVP
Crhr1 12921 GPCR-CRH
Celsr2 53883 GPCR-flamingo type EC domain
Gcgr 14527 GPCR-glucagon
Gpr48 107515 GPCR-LGR4
Lhcgr 16867 GPCR-LH
Mtnr1b 244701 GPCR-Melatonin
Olfr15 18312 GPCR-olf
Olfr152 258640 GPCR-olf
Olfr42 18341 GPCR-olf
P2ry6 233571 GPCR-pyrimidinergic
Tact3 21338 GPCR-tachykinin
Vipr1 22354 GPCR-VIP
Fzd3 14365 GPCR-Wnt
Impa2 114663 intracellular signaling-inositol(myo)-1(or 4)-monophosphatase 2
Mapk8ip2 60597 intracellular signaling-kinase scaffold
Plcg1 18803 intracellular signaling-phospholipase C, gamma 1
Pde1b 18574 intracellular signaling- CM-dependent Pde1B
Orai2 269717 intracellular signaling-Ca++ release-activated Ca++ channel
Itpkc 233011 intracellular signaling-inositol-trisphosphate 3-kinase C
Ikbkb 16150 intracellular signaling-NFKB pathway
Seh1l 72124 intracellular signaling-NPC Nup107–160 complex; GATOR2 complex
Ptpdc1 218232 intracellular signaling-protein tyrosine phosphatase domain containing 1
Rac1 19353 intracellular signaling-small GTPase
Bcar3 29815 intracellular signaling; SH2 domain
Calb1 12307 intracellulat signaling-cytosolic Ca++ binder/buffer
Akap7 268287 intrecellular signaling-PKA anchor protein
Ccl4 20303 ligand-chemokine
Vwc2 319922 ligand-secreted BMP antagonist
Srpx2 68792 matrix-Chondroitin sulfate proteoglycan
Dspp 13517 matrix-dentin sialophosphoprotein
Cln3 12752 membrane structure-lysosomal
Nsmaf 18201 membrane structure-neutral sphingomyelinase activation associated factor
Pik4cb 107650 membrane structure-phosphatidylinositol 4-kinase, beta
Tjp2 21873 membrane structure-tight junction protein
Slc35f1 215085 membrane transport-?nucleotide sugars
Slc44a4 70129 membrane transport-thiamine pyrophosphate transporter.
Pfkfb3 170768 metabolism-6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Coasy 71743 metabolism-CoA synthase
Gpx2 14776 metabolism-glutathione peroxidase 2
Pank4 269614 metabolism-pantothenate kinase 4
Galntl4 233733 metabolism-polypeptide N-acetylgalactosaminyltransferase 18
Tpk1 29807 metabolism-thiamin pyrophosphokinase 1
Nfu1 56748 mitochondria-NFU1 iron-sulfur cluster scaffold homolog
Aldh18a1 56454 mitochondrial-proline, ornithine and arginine biosynthesis
Pink1 68943 mitochondrial-protein kinase
Ufd1l 22230 protein degradation-modification
Cdk3 69681 protein kinase-cell cycle regulation
Irak3 73914 protein kinase-IL1 receptor associated
Pim2 18715 protein kinase-overlaps specificity of Akt
Ripk5 213452 protein kinase-DUSTY like
Src 20779 protein kinase-tyrosine
Stk23 56504 protein kinase-SRSF proteins
Map4k3 225028 protein kinase-GLK
Map4k1 26411 protein kinase-HPK1
Map3k10 269881 protein kinase-MLK2
Rps6kb1 72508 protein kinase-S6
Cd3e 12501 receptor-T cell Ag
Acvr2 11480 receptor-ActivinA type
Fgfr3 14184 receptor-FGF
Cd244 18106 receptor-NK cell
Cd8a 12525 receptor-T cell
Rbm12 75710 RNA binding protein
Tdrd12 71981 RNA-piRNA biogenesis factor
Rpp25 102614 RNA-ribonuclease P subunit
Tnrc6 233833 RNA-RNAi and miRNA
Tars2 71807 RNA-Tars2 threonyl-tRNA synthetase 2, mitochondrial (putative)
Eif2b3 108067 RNA-translation initiation factor
Bhlhb9 70237 transcription factor
Nrbp 192292 transcription- nuclear receptor binding protein 1
Ccdc134 76457 Transcription-Cotranscriptional regulator-? Secreted protein
Tlx3 27140 transcription-homeobox protein
Med25 75613 Transcription-mediator of RNA polymerase II transcription, subunit 25
Smr3a 20599 submaxillary gland androgen regulated protein 3A
Sbsn 282619 unknown
Trabd 67976 unknown-TraB domain containing, TRABD