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The chemical structure and cytotoxicity of PLB toward PC-3 and DU145 cells.
Notes: (A) The chemical structure of PLB. (B) PC-3 and DU145 cells treated with PLB at concentration ranging from 0.1 μM to 20 μM for 24 hr and 48 hr, respectively. The cell viability was determined by the MTT assay.
Abbreviations: hr, hour; IC50, half maximal inhibitory concentration; MTT, thiazolyl blue tetrazolium bromide; PLB, plumbagin.
