Table 1.
Characteristics of study participants (n = 3417) by anti-HTN medication use
| Characteristics | Nonusers (n = 1425) | Anti-HTN medication users (n = 1992) | p |
|---|---|---|---|
| Male, n (%) | 662 (46.5) | 768 (38.6) | <0.001 |
| Age, (y) mean ± SD | 74.2 ± 6.5 | 74.9 ± 6.4 | 0.002 |
| Education, (y) mean ± SD | 13.6 ± 2.9 | 13.2 ± 2.9 | 0.002 |
| Smoking habits, n (%)a | |||
| Nonsmoker | 1138 (80.0) | 1619 (81.4) | 0.006 |
| Ever smoker | 237 (16.7) | 336 (16.9) | |
| Current smoker | 48 (3.4) | 33 (1.7) | |
| Drinking habits, n (%)a | |||
| Nondrinker | 1193 (83.9) | 1674 (84.2) | 0.515 |
| Ever drinker | 167 (11.7) | 243 (12.2) | |
| Current drinker | 62 (4.4) | 72 (3.6) | |
| Number of ε4 alleles, n (%)a | |||
| 0 | 938 (66.7) | 1392 (70.3) | 0.065 |
| 1 | 434 (30.9) | 538 (27.2) | |
| 2 | 35 (2.5) | 50 (2.5) | |
| Prevalence of vascular risk factors, n (%)a | |||
| Hypertension | 341 (33.2) | 1582 (85.1) | <0.001 |
| High cholesterol | 476 (46.3) | 985 (61.2) | <0.001 |
| Diabetes mellitus | 151 (15.6) | 486 (32.0) | <0.001 |
| Stroke | 82 (8.9) | 260 (17.9) | <0.001 |
| CABG | 63 (6.9) | 273 (18.6) | <0.001 |
| MI | 108 (11.4) | 446 (29.4) | <0.001 |
| Alzheimer’s disease, n (%) | 159 (11.2) | 166 (8.3) | 0.003 |
Key: CABG, coronary artery bypass graft; MI, myocardial infarction; SD, standard deviation.
a
This is the percentage of the total number with non-missing data.