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. 2015 Mar 19;10(3):e0117074. doi: 10.1371/journal.pone.0117074

Table 6. Enriched cell adhesion proteins tagged by biotin ligase fused to occludin and claudin-4.

Accession Name Localization/Function-Cell Adhesion OCLN N OCLN C CLD4 N ZO-1 N ZO-1 C E-CAD Reference
308081450 CD44 antigen precursor Mediates cell-cell and cell-matrix interactions. 13.6 7.4 57.9 ND 7.4 (0.8)
345803763 Leucine-rich repeat transmembrane protein FLRT2 May have a function in cell adhesion and/or receptor signaling. 7.4 2.8 8.6 ND 2.8 ND
147898773 Carcinoembryonic antigen-related cell adhesion molecule 1 precursor Membrane protein that mediate intercellular adhesion, proliferation, angiogenesis, apoptosis, immune responses, T cell cytotoxicity, differentiation, and polarization. 7.1 ND 34.5 ND ND 3.5 [122]
74004342 345797211 Plakophilin-4 Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques. 6.8 3.8 4.2 ND ND 3.0
345793345 Integrin beta-1 Cell adhesion to exracellular matrix. 6.6 2.1 43.6 ND 2.1 ND
147904030 Carcinoembryonic antigen-related cell adhesion molecule 28 precursor Cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. 6.6 2.7 15.3 ND 2.7 ND
359318970 359318968 Protocadherin-1-like Involved in cell-cell interaction and cell adhesion. 4.4 3.1 9.6 ND 3.1 ND
345796205 Immunoglobulin superfamily member 11 Functions as a cell adhesion molecule through homophilic interaction. 3.8 2.9 (3.3) 4.8 2.9 ND
359319033 Protein LAP2-like Found in hemidesmosomes, which are cell-substrate adhesion complexes in stratified epithelia. 3.5 5.5 (1.0) 3 ND ND
50950141 Presenilin-1 Probable catalytic subunit of the gamma-secretase complex. May play a role in intracellular signaling and gene expression. Stimulates cell-cell adhesion though its association with the E-cadherin/catenin complex. 2.9 (1.6) (1.6) ND ND (0.8)
345799149 Integrin alpha-2 Cell adhesion to exracellular matrix. (2.6) (0.6) 32.6 ND ND ND
66472883 Podocalyxin precursor Pro-adhesive protein, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. (1.7) (0.4) 17.48 ND ND ND
73991135 Leucine-rich repeat transmembrane protein FLRT3 Cell adhesion and/or receptor signaling. (1.2) ND 6.2 ND ND ND
50978890 Integrin beta-3 precursor Cell adhesion to exracellular matrix. ND ND 10.2 ND ND ND