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. 2015 Mar 19;10(3):e0116296. doi: 10.1371/journal.pone.0116296

Fig 4. Minimum control event rate (CERmin) for preeclampsia with varying treatment event rates (TER) for preeclampsia at fixed values of 0.05 (black) and 0.52 (grey) quality-adjusted life years (QALYs) gained with ASA prophylaxis in pregnancy [1], and varied by two direct costs (DC) of ASA: $10 (actual cost, triangles) and $1 000 (circles).

Fig 4

CERmin calculated as: TER + [DC / (QALYs gained x $50 000)]. At a TER of 6.0% and a DC of ASA of $10, the CERmin for preeclampsia is essentially the same as the TER with 0.05 or 0.52 QALYs gained (6.4% and 6.0%, respectively). At a TER of 6.0%, but a DC of ASA of $1000, the CERmin increases to 9.8% with 0.52 QALYs gained (dashed blue lines) and 46.0% with 0.05 QALYS gained (dashed red lines).