Table 3. Association between SNPs in the TPCN2/MYEOV region and melanoma.
| Table 3a) | p-heterogeneity | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| SNP | Gene, Chromosome / coded allele, Previous trait | Sex | # Studies | n | OR | 95% CI | p-value | Between-studies | Between-sexes |
| rs12418451 | TPCN2, MYEOV (near) | Combined | 5 | 22,053 | 1.11 | (1.03–1.19) | 5.03E-03 | 0.30 | |
| 11 / A | Male | 3 | 8,213 | 1.22 | (1.09–1.37) | 7.96E-04 | 0.21 | 0.04 | |
| Prostate cancer | Female | 4 | 13,840 | 1.05 | (0.96–1.14) | 0.33 | 0.42 | ||
3a) Association between SNP rs12418451 melanoma, both overall and stratified by sex.
3b) Four additional SNPs within the same locus as rs12418451, shown for comparison (r2 with rs12418451 < 0.13 in 1000G CEU).