Skip to main content
. 2015 Mar 19;10(3):e0115997. doi: 10.1371/journal.pone.0115997

Fig 3. OPC transplantation promotes NSC proliferation in the SVZ and the DG of the hippocampus following HI.

Fig 3

(A, C) Proliferating NSCs (white arrows) were visualized by double immunolabeling with antibodies against BrdU (red) and Nestin (green). (B, D) The number of BrdU+/Nestin+ proliferating NSC increased in HI animals (HI+PBS) compared to sham-operated controls; injection of OPCs (HI+OPC) potentiated this effect. Data are expressed as mean ± SD. *P < 0.05, **P < 0.01, HI group vs. sham controls; #P < 0.05, ##P < 0.01 between HI+PBS and HI+OPC groups; n = 6–8 animals per group. Scale bar = 50μm.