Schematic diagram illustrating the different elements of the endosomal-lysosomal and autophagy pathways and their relationship to Cathepsin D (Cat D), rabaptin5, rabs (4, 5 and 7), mTOR, p62 and traf6 proteins. E. Reticulum, endoplasmic reticulum. mTOR, mammalian target of rapamycin.