Figure 3.

Representative immunoblots and box plots of total levels of hippocampal phosphorylated mTORs (pmTORs2448 and pmTORs2481) and total mTOR in cases clinically diagnosed as NCI, MCI and AD. β-tubulin was used to normalize the immunoreactive signals obtained by densitometry in the blots. (A–C) Levels of pmTORs2448 (A), pmTORs2481 (B) and total mTOR (C) revealed no statistical differences across the clinical groups. NCI, non-cognitive impairment, MCI, mild cognitive impairment, AD, Alzheimer disease. mTOR, mammalian target of rapamycin. Circles in the box plots indicate outliers.