Table 5.
Summary of AT8-immunoreactive hippocampal neurofibrillary tangle density by clinical diagnosis
| NCI | MCI | AD | P-valuea | Pair-wise comparison | ||
|---|---|---|---|---|---|---|
| CA1 | Median (Range) | 7.0* (0–39.0) | 18.0 (0–44.0) | 32.5 (2–59.0) | 0.13 | -- |
| CA2/3 | Median (Range) | 7.0 (0–36.0) | 8.5 (0–21.0) | 18.0 (8.0–30.0) | 0.12 | -- |
| Hilus | Median (Range) | 3.0 (0–14.0) | 1.0 (0–11.0) | 11.0 (0–35.0) | 0.17 | -- |
*
Median NFT density (number/mm2).
a
Kruskal-Wallis test, with Dunn’s correction for multiple comparisons.
NCI, no cognitive impairment, MCI; mild cognitive impairment; AD, Alzheimer disease.