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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Circ Heart Fail. 2014 Dec 30;8(2):352–361. doi: 10.1161/CIRCHEARTFAILURE.114.001893

Figure 3. Cell-specific expression of TNF and TNFR1.

Figure 3

Ang-II-treated WT hearts were either stained with fluorescence-labeled antibodies (blue = nuclear DAPI) (qualitative), or used for cytometry (quantitative). A-D: Representative images for TNF expression above their quantitative data, both indicating that TNF was highly expressed by CD45+ (A1/A2) and CD86+ cells (B1/B2), but not by CD301+ (C1/C2) or CD206+ (D1/D2) cells. E-H: TNFR1 was expressed by most cells including CD45+ (E1/E2), CD86+ (F1/F2), CD301+ (G1/G2), and CD206+ (H1/H2) cells. Statistics: (*) indicates a statistically significant difference between saline-treated (n=3-4) and Ang-II-treated (n=6) WT groups (two-tailed Mann-Whitney). NS: not significant.