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The effect of pressure pain testing on fatigue was assessed in all study subjects. The subjects received trains of 200 kPa and 400 kPa pressure stimuli to the forearms for 10 s each. Fatigue was assessed at baseline and after pressure pain testing using the VAS (0-10). Fatigue ratings of CFS subjects were significantly higher than NC ratings. Fatigue ratings significantly decreased after pressure pain testing but this effect was not significantly different between NC and CFS subjects.
