. Author manuscript; available in PMC: 2016 Apr 1.

Published in final edited form as: Anesthesiology. 2015 Apr;122(4):806–820. doi: 10.1097/ALN.0000000000000583

Table 2.

Biophysical Variables of A341V Constructs and Corresponding Wild-type IKs in HL-1 cardiomyocytes

	V_0.5		k		n
	control	isoflurane	control	isoflurane	n
KCNQ1+KCNE1	29.4 ± 1.7	30.2 ± 1.6	12.3 ± 0.5	12.2 ± 0.7	8
A341V+KCNE1	41.5 ± 1.0	38.8 ± 1.6 ^§	5.4 ± 1.0	7.7 ± 1.0 ^§	8
2KCNQ1+KCNE1	22.8 ± 1.7	25.6 ± 1.8 ^§	14.6 ± 0.6	13.6 ± 0.6 ^§	10
A341V+KCNQ1+KCNE1	31.1 ± 1.4	31.3 ± 1.1	11.7 ± 0.5	11.5 ± 0.4	8

V_0.5 (voltage of half-maximal activation) and k (slope factor) were determined as described in Materials and Methods under Data Analysis and Statistical Analysis. Statistical comparisons were performed between control and isoflurane within the same group. Data are presented as mean ± SE.

^§

P < 0.05 vs. control