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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: J Invest Dermatol. 2014 Dec 18;135(4):1089–1097. doi: 10.1038/jid.2014.528

Figure 5. BAP1 overexpression in Pmel and melanomas.

Figure 5

(a) Effects of BAP1 overexpression (BAP1 OE) and depletion (shBAP1) on Pmel proliferation, survivin levels and colony forming capacity. Both BAP1 elevation and suppression in Pmel cells were associated with a decrease in colony formation, proliferation and levels of survivin. (b) Overexpression of BAP1 in 3 melanoma lines had more stimulatory effects on proliferation and survivin. The experiments were performed 3 times with similar results; *p<0.05, **p<0.01 by student T test.